As per the World Health Organization, neuropsychiatric disorders contribute to 20% of the global burden related to illness-induced disability. These disorders are intricate conditions affecting brain functionality. They encompass a range of intricate brain-related conditions such as depression, bipolar disorder, anxiety disorders, schizophrenia, substance abuse disorders, developmental disorders like autism, and neurodegenerative conditions like Alzheimer’s dementia. Our research team is dedicated to investigating psychiatric disorders, particularly focusing on schizophrenia and depression. We employ diverse methodologies including brain imaging, genetics, neuropsychopharmacology, neurophysiology, and behavioral phenotyping using animal models. Through these approaches, we aim to enhance our comprehension of the origins and underlying mechanisms of these disorders.
Synaptic localization of susceptibility genes
A custom startle apparatus based on mechanical (tap) stimuli was designed to assess startle habituation in the schizophrenia model of larval zebrafish
Team members:
- Dr. Tang Pek Yee (Leader)
- ChM. Ts. Dr. Tee Shiau Foon
- Dr. Mok Siew Ying
- Dr Lee Poh Foong